How to choose a biological safety cabinet

Do you know how to buy a biosafety cabinet? Let us take a look today

 

When choosing a biological safety cabinet, the laboratory should understand the main elements of the biological safety level involved in the work of infectious microorganisms, and select different levels of biological safety cabinets according to the protection provided to individuals, the environment, and the society.

 

Biosafety Level 1 (BSL-1): Suitable for very familiar disease sources, which do not often cause diseases in healthy *****s, and have little potential risk to experimenters and the environment. The laboratory does not need to be distinguished from general walking in buildings Generally, work is carried out on open laboratory benches in accordance with standard hierarchical biological operations. No special suppression equipment and facilities (biological safety cabinets) are generally required or used.

 

Biosafety Level 2 (BSL-2): Suitable for disease sources that are potentially dangerous to humans and the environment. The difference from BSL-1 is:

 

① All laboratory personnel should have received special training in the treatment of the source of the disease, and should be guided by qualified workers.

 

② Restrict entry into the laboratory when conducting experiments.

 

③ Special attention should be paid to contaminated sharps.

 

④ Certain processes that may produce infectious aerosols or splashes should be carried out in biological safety cabinets or other physical restraint equipment, and class I and II biological safety cabinets can be used.

 

Biosafety Level 3 (BSL-3): Used in clinical, diagnostic, teaching, research or production facilities, and work on endogenous and exogenous pathogens is carried out at this level. Inhalation of the pathogen due to exposure can cause serious and potentially fatal diseases.

 

Laboratory personnel should be professionally trained in dealing with pathogenic pathogens that may cause death, and be supervised by qualified scientists who have experience in working with the pathogen.

 

All steps related to the operation of the source of infection are carried out in a biological safety cabinet or other physical suppression device. The biological safety cabinet of grade 2 or above is selected. The laboratory needs special design and construction, and the indoor is negative pressure.

 

Biosafety Level 4 (BSL-4) is used for dangerous pathogens or exogenous pathogens that are highly dangerous to life. It can cause laboratory infection or unknown risk of infection through aerosol, and cause fatal related pathogens, should choose three-level biological safety cabinet and positive pressure protective clothing, such as SARS virus has a moderate potential risk to humans or the environment, it is The processing of virus patient samples should be carried out in a biosafety level 2 (BSL-2) or above laboratory. In order to provide effective protection for operators and the environment and samples, the laboratory should use level 2 or above Wind-type biological safety cabinet (B2 type).
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