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Air sampler

日期:2023-02-06 20:32
浏览次数:57
摘要:The plankton sampler is suitable for the air microorganism detection in pharmaceutical GMP factory, dairy factory, hospital operating room, biological cleaning, fermentation industry and other clean rooms and sterile environment, as well as the relevant research and teaching departments for air microorganism sampling research. As a commonly used testing instrument, it can accurately reflect the microbial concentration in the clean room, with the advantages of large sampling volume, stable perfor
The plankton sampler is suitable for the air microorganism detection in pharmaceutical GMP factory, dairy factory, hospital operating room, biological cleaning, fermentation industry and other clean rooms and sterile environment, as well as the relevant research and teaching departments for air microorganism sampling research. As a commonly used testing instrument, it can accurately reflect the microbial concentration in the clean room, with the advantages of large sampling volume, stable performance, easy operation, etc. It is designed according to the principle of particle impact and the isometric sampling theory. The sampling is direct, the wind speed at the sampling port is basically consistent with that in the clean room, and can accurately reflect the microbial concentration in the clean room. The air of dusty bacteria passes through the micropores at a high speed and is impacted on the AGAR surface in the petri dish. In the process of culture, these living microorganisms undergo a dynamic rehydration process and grow at a high speed, thus achieving fast results.



Food safety, medical safety and other matters related to the vital interests of the people's livelihood are getting more and more attention, so the production enterprises and public institutions have high requirements. Among the standards of manufacturing enterprises, the more strict is the "Good Practice for the Quality Management of Pharmaceutical Production", referred to as the GMP standard. Among them, for the biological cleanliness requirements of the air cleanliness of the production workshop, it is required to detect the plankton and settling bacteria items at the same time. Other food factories, infant formula dairy plant, hospital operating room, fermentation industry clean room, etc., also slowly from the single detection of settling bacteria to the strict bidirectional detection of plankton and settling bacteria GMP standards.



As we know, bacteria can not exist alone in the air, often attached to the surface of dust particles several times larger than them, so the bacteria suspended in the air or settled on the ground. They are actually biological particles carrying bacteria, so the relationship between plankton-settling bacteria is the relationship between plankton-settling biological particles and settling biological particles. Although the concentration of natural atmospheric particulates, including biological particulates, varies over time and place, the particle size distribution is generally the same. Therefore, it can be considered that there is a correlation between planktonic bacteria and settling bacteria in the natural atmosphere without wind, and the settling bacteria value can be used to calculate the concentration of planktonic bacteria. However, in the biological clean room, the particle size distribution of bacteria-carrying particles is different from that in the natural atmosphere, and there is also the influence of air supply, so the relationship between plankton-settling bacteria is definitely different from that in the natural atmosphere.



The internal conditions of biological clean rooms with different uses are different, and the relationship between plankton and settling bacteria is impossible to be consistent. For pharmaceutical biological clean workshop, its production characteristics not only make it different from other biological clean rooms, but also the production of different types of drugs in the clean workshop, its process is different, so it can not use the general biological clean room plankton and settling bacteria to reflect the relationship between the two in the pharmaceutical biological clean workshop.



Through the sampling experiment data of plankton bacteria and sinking bacteria in the workshop by the plankton bacteria sampler, it can be concluded that:



In different types of biological clean pharmaceutical workshops, the relationship between the concentration of plankton and the number of settling colonies is related to the specific production process, air flow organization form, ventilation times, personnel conditions and other factors, and the difference is very large, it is difficult to find the common rule, the relationship between the two control indicators in GMP design Specification fully reflects this point.



Therefore, in a general sense, due to the uncertain relationship between the concentration of plankton and the number of settling colonies, the amount of settling bacteria in the pharmaceutical workshop can only indicate the surface microbial pollution. The amount of plankton reflects the concentration of biological particles in the air in the workshop. In order to fully reflect the degree of microbial pollution in the workshop, two indexes of settling bacteria and settling bacteria need to be tested at the same time. Therefore, for food factories, dairy factories, operating rooms, fermentation industry clean rooms, etc., two indexes of settling bacteria and settling bacteria need to be tested at the same time in air cleanliness detection.